Scientist (m/f/d) - Chemical hazard indicators “toxicity and persistent toxicity” with new approach methodologies (case study 3)
The job
The Department of Cell Toxicology invites, in subject of the final approval of the third-party-funded project, applications for a full-time positions (100%) over 24 months as a Scientist (f/m/x). You work in the project CoModHaz (Co-Creation process for the modernization of chemical hazard indicators), which has the goal to implement a new hazard assessment concept (doi:10.1007/s00204-023-03485-5) based on NAMs (new approach methodologies). CoModHaz sets out to bring this novel concept into practice and test it on challenging use cases developed in a co-creation process with five practice partners from regulation (national authorities), NGOs and industry.Place of work
LeipzigWorking time
100% (39h/week)Contract limitations
limited contract / 24 months. Start date September 2024 to January 2025.Salary
Remuneration according to the TVöD public-sector up to pay grade Depending on personal requirements up to EG 14 including attractive public-sector social security benefits.Contact
Your contact for any questions you may have about the job:
Phone: (+49) 0341 6025 1244
Beate.escher@ufz.de
The UFZ
The Helmholtz Centre for Environmental Research (UFZ) with its 1,100 employees has gained an excellent reputation as an international competence centre for environmental sciences. We are part of the largest scientific organisation in Germany, the Helmholtz association. Our mission: Our research seeks to find a balance between social development and the long-term protection of our natural resources.
The job
The Department of Cell Toxicology invites, in subject of the final approval of the third-party-funded project, applications for a full-time positions (100%) over 24 months as a Scientist (f/m/x). You work in the project CoModHaz (Co-Creation process for the modernization of chemical hazard indicators), which has the goal to implement a new hazard assessment concept (doi:10.1007/s00204-023-03485-5) based on NAMs (new approach methodologies). CoModHaz sets out to bring this novel concept into practice and test it on challenging use cases developed in a co-creation process with five practice partners from regulation (national authorities), NGOs and industry.
Your tasks
- You are responsible and perform one of four case studies in the project CoModHaz
- You will develop the toxicity screening parameter CTE (cumulative toxicity equivalents) for plastic additives
- You will couple the biodegradation assay to the toxicity assay to derive the PTE (persistent toxicity equivalents) for plastic additives
- You will work with a bioassay test battery convering the six clusters of human disease
- You screen defined mixtures of plastic chemicals and UVCBs
- You collaborate with CoModHaz team members, collaboration partners at Eawag, Switzerland, and projects partners from industry, regulation (national authorities), NGOs and academia
- You work with a team of toxicologists to make high-throughput in vitro bioassays applicable for hazard assessment of chemicals and perform a case study
- You work on coupling high-throughput biodegradation assay with the bioassays to quantify “persistent toxicity”
- You apply and partially implement in vitro bioassays targeting cytotoxicity, neurotoxicity, carcinogenicity, mutagenicity and reproduction toxicity (CMR) and endocrine disruption (ED).
- You present results at international conferences and prepare publications in peer-reviewed scientific journals.
We offer
- The opportunity to work in interdisciplinary, international teams and benefit from a variety of perspectives
- Collaboration with practise partners with possibility to do short secondments at the practise partners
- Work in interdisciplinary, multinational teams and excellent links with national and international research networks
- Excellent research infrastructure and research data management to optimally support your work
- Flexible working hours and a wide range of options for balancing work and care responsibilities through our family office
- Competent support and advice for international colleagues arriving at the UFZ from the 'International Office'
- Special annual payment, capital-forming benefits and subsidised Germany Job Ticket
- A workplace in a vibrant region with a high life quality and social and cultural diversity
Your profile
- A Master or PhD in environmental sciences, (eco)toxicology, biology, (analytical) chemistry, bioanalysis or related areas
- Research experience with in vitro bioassays, human toxicology or ecotoxicology essential
- Experience with analytical chemistry desirable
- High degree of organisation and ability to work independently
- Excellent interpersonal and oral/written communication skills (English required, German desirable)
- Motivation to work in an interdisciplinary team within an international project.